omicwas - Cell-Type-Specific Association Testing in Bulk Omics Experiments
In bulk epigenome/transcriptome experiments, molecular
expression is measured in a tissue, which is a mixture of
multiple types of cells. This package tests association of a
disease/phenotype with a molecular marker for each cell type.
The proportion of cell types in each sample needs to be given
as input. The package is applicable to epigenome-wide
association study (EWAS) and differential gene expression
analysis. Takeuchi and Kato (submitted) "omicwas:
cell-type-specific epigenome-wide and transcriptome association
study".
